Description

Benzonitrile, 3-Bromo-5-Chloro-4-Hydroxy- is a halogenated and hydroxylated benzonitrile derivative, serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its precise substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable source of high-purity, structurally defined intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with specific electronic or photonic properties.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for fine chemical and custom synthesis houses serving diverse R&D needs.

Basic Information

Product Name	Benzonitrile, 3-Bromo-5-Chloro-4-Hydroxy-
CAS No.	1689-86-7
Molecular Formula	C7H3BrClNO
Molecular Weight	232.46 g/mol
Synonyms	3-Bromo-5-chloro-4-hydroxybenzonitrile; 4-Hydroxy-3-bromo-5-chlorobenzonitrile; 5-Chloro-3-bromo-4-hydroxybenzonitrile; 2-Bromo-6-chloro-3-cyanophenol; Benzonitrile, 4-hydroxy-3-bromo-5-chloro-; 1689-86-7; 3-Bromo-5-chloro-4-hydroxy-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Chloro-4-Hydroxybenzonitrile is produced under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.