Description

(9S)-6'-Methoxycinchonan-9-Ol Monohydrochloride CAS NO 1668-99-1 is a high-purity, chiral alkaloid derivative, specifically the monohydrochloride salt of the (9S)-enantiomer of 6'-methoxycinchonan-9-ol. This compound is a critical intermediate and chiral building block in the synthesis of advanced pharmaceuticals and fine chemicals, valued for its defined stereochemistry and high chemical purity. It is primarily required by research institutions, pharmaceutical development laboratories, and manufacturers of active pharmaceutical ingredients (APIs) for applications in asymmetric synthesis and as a precursor to specialized catalysts and therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly in the development of antimalarial and antiarrhythmic agents.
• Asymmetric Catalyst Synthesis: Used to prepare chiral ligands and organocatalysts for enantioselective chemical reactions in fine chemical production.
• Analytical Reference Standard: Serves as a high-purity standard for quality control and method development in pharmaceutical analysis using HPLC, LC-MS, or NMR.
• Biochemical Research: Employed in academic and industrial research to study enzyme inhibition, receptor binding, and other chiral recognition processes.
• Fine Chemical Synthesis: A versatile building block for creating specialty chemicals with specific stereochemical requirements.

Basic Information

Product Name	(9S)-6'-Methoxycinchonan-9-Ol Monohydrochloride
CAS No.	1668-99-1
Molecular Formula	C₂₀H₂₅ClN₂O₂
Molecular Weight	360.88 g/mol
Synonyms	(9S)-6'-Methoxycinchonan-9-ol Hydrochloride; (9S)-6'-Methoxycinchonan-9-ol HCl; (9S)-9-Hydroxy-6'-methoxycinchonan Monohydrochloride; (9S)-Cinchonan-9-ol, 6'-methoxy-, monohydrochloride; (8α,9S)-6'-Methoxycinchonan-9-ol Hydrochloride; 6'-Methoxy-(9S)-cinchonan-9-ol Hydrochloride; Hydroquinidine Hydrochloride (related stereoisomer); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (9S)-6'-Methoxycinchonan-9-Ol Monohydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (9S-enantiomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.