Description

Methane, Trifluoroisothiocyanato- is a specialized fluorinated building block of significant interest in advanced chemical synthesis. This compound, identified by CAS No. 1656-56-0, is valued for its unique reactivity, particularly the isothiocyanate (-NCS) group adjacent to a trifluoromethyl moiety. It serves as a critical precursor for introducing the SCN-CF3 unit into target molecules, enabling the development of novel materials and bioactive compounds. Key industries requiring this high-value intermediate include pharmaceutical research, agrochemical development, and advanced material science.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those requiring fluorinated heterocycles or thiourea derivatives for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key reagent for creating new pesticides and herbicides with the SCN-CF3 functional group, which can impart unique biological activity and environmental persistence profiles.
• Material Science Precursor: Employed in the development of advanced polymers, liquid crystals, or organic electronic materials where the incorporation of fluorine and sulfur atoms can modify physical properties.
• Chemical Research & Development: Acts as a versatile electrophile in organic synthesis for constructing complex molecules, useful in methodology development and discovery chemistry.
• Ligand and Catalyst Design: Utilized to prepare specialized ligands for metal complexes or organocatalysts, leveraging the electron-withdrawing nature of the CF3 group.

Basic Information

Product Name	Methane, Trifluoroisothiocyanato-
CAS No.	1656-56-0
Molecular Formula	C2F3NS
Molecular Weight	127.09 g/mol
Synonyms	Trifluoromethyl isothiocyanate; Isothiocyanic acid, trifluoromethyl ester; Trifluoroacetonitrile sulfide; CF3NCS; 1-Isothiocyanato-1,1,1-trifluoromethane; Trifluoromethanethiocyanate; Perfluoromethyl isothiocyanate
EINECS	Contact for details

Quality Control

Every batch of Methane, Trifluoroisothiocyanato- is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to ensure traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at temperatures between 2°C and 8°C. The container should be kept upright and securely sealed to prevent pressure build-up and moisture ingress. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.