Description

2-Fluoro-3-Sodiooxyacrylic Acid Ethyl Ester is a specialized fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the preparation of complex molecules, particularly in pharmaceutical research and agrochemical development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce unique fluorinated motifs into target structures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing fluorinated heterocycles or acrylate derivatives.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced materials with tailored surface properties.
• Fluorination Chemistry: Acts as a reagent in methodologies for introducing fluorine-containing functional groups into organic molecules under controlled conditions.
• Cross-Coupling Reactions: Utilized as a substrate in palladium-catalyzed and other metal-mediated coupling reactions to construct complex molecular architectures.

Basic Information

Product Name	2-Fluoro-3-Sodiooxyacrylic Acid Ethyl Ester
CAS No.	1652-39-7
Molecular Formula	C5H6FNaO4
Molecular Weight	172.09 g/mol
Synonyms	Ethyl 2-fluoro-3-(sodiooxy)acrylate; Sodium 2-fluoro-3-ethoxy-3-oxoprop-1-en-1-olate; 2-Fluoro-3-hydroxyacrylic acid ethyl ester sodium salt; Ethyl (Z)-2-fluoro-3-hydroxyacrylate sodium salt; 2-Fluoro-3-sodiooxy-acrylic acid ethyl ester; Acrylic acid, 2-fluoro-3-hydroxy-, ethyl ester, sodium derivative; (Z)-Ethyl 2-fluoro-3-hydroxyacrylate sodium salt
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Sodiooxyacrylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.