Description

1-Bromo-3,3-Dimethylbutane is a versatile tertiary alkyl bromide, also known as tert-butyl bromide, valued for its role as a key alkylating agent and building block in organic synthesis. Its structure makes it a crucial intermediate for introducing the bulky tert-butyl group into target molecules, enabling the synthesis of complex pharmaceuticals, agrochemicals, and advanced materials. This compound is essential for research chemists and production facilities in the pharmaceutical, specialty chemical, and material science industries seeking reliable, high-purity intermediates.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) where the tert-butyl moiety is required for biological activity or to modulate pharmacokinetic properties.
• Agrochemical Synthesis: Serves as a key alkylating agent in the production of herbicides, fungicides, and other crop protection agents.
• Material Science & Polymer Chemistry: Employed as a monomer or chain transfer agent in the development of specialty polymers and advanced materials.
• Organic Synthesis Reagent: A fundamental reagent for nucleophilic substitution (SN1) reactions, facilitating the introduction of the tert-butyl group into various organic frameworks in research and development.
• Ligand & Catalyst Preparation: Used in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Flavor & Fragrance Industry: Acts as a precursor in the synthesis of certain aroma chemicals and flavor compounds.

Basic Information

Product Name	1-Bromo-3,3-Dimethylbutane
CAS No.	1647-23-0
Molecular Formula	C6H13Br
Molecular Weight	165.07 g/mol
Synonyms	tert-Butyl Bromide; 2-Bromo-2-methylpropane; Trimethylbromomethane; (CH3)3CBr; tert-C4H9Br; 1-Bromo-tert-butane; 2-Methyl-2-bromopropane; Neohexyl Bromide
EINECS	216-713-0

Quality Control

Our 1-Bromo-3,3-Dimethylbutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and industrial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed to prevent evaporation and moisture ingress. Recommended storage temperature is 2-8°C for extended stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Acidity (as HBr)	≤ 0.05%
Specific Gravity (20°C)	1.220 - 1.235
Refractive Index (n20/D)	1.428 - 1.432

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.