Description

1,4-Dibromo-2,3,5,6-Tetramethylbenzene is a high-purity, multi-substituted aromatic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its dual bromine functionality, which provides excellent reactivity for cross-coupling reactions and further functionalization. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require precise, reliable intermediates for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the tetramethyl-substituted benzene core contributes to specific biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and organometallic chemistry.
• Organic Electronic Materials: A valuable monomer or intermediate in the production of organic semiconductors, hole-transport materials, and other components for OLEDs and photovoltaic devices.
• Polymer Modification: Incorporated into polymer backbones to alter physical properties such as thermal stability, refractive index, or solubility for high-performance plastics and resins.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and constructing complex polycyclic aromatic structures.

Basic Information

Product Name	1,4-Dibromo-2,3,5,6-Tetramethylbenzene
CAS No.	1646-54-4
Molecular Formula	C10H12Br2
Molecular Weight	292.01 g/mol
Synonyms	1,4-Dibromodurene; Durene, 1,4-dibromo-; 2,3,5,6-Tetramethyl-1,4-dibromobenzene; 1,4-Dibromo-2,3,5,6-tetramethyl-benzene; NSC 404087; Durene Dibromide; Tetramethyl-p-dibromobenzene; p-Dibromodurene
EINECS	Contact for details

Quality Control

Our 1,4-Dibromo-2,3,5,6-Tetramethylbenzene is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	168°C - 172°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.