Description

6-Mercaptohexan-1-ol is a versatile bifunctional organic compound featuring both a terminal thiol (mercapto) and a terminal hydroxyl group. This unique structure makes it a valuable intermediate for synthesizing heterobifunctional crosslinkers, surface modifiers, and functional polymers. It is particularly sought after by researchers and manufacturers in the life sciences and advanced materials sectors. The compound is also known by its CAS number 1633-78-9.

Application

• Bioconjugation & Crosslinking Agent: Used to create stable thioether bonds with proteins, peptides, or other biomolecules, while the hydroxyl group allows for further functionalization or attachment to surfaces.
• Surface Modification & Self-Assembled Monolayers (SAMs): The thiol group binds to gold, silver, and other metal surfaces, creating functionalized monolayers used in biosensors, nanotechnology, and corrosion inhibition.
• Polymer & Material Science: Serves as a chain transfer agent (CTA) in reversible addition-fragmentation chain-transfer (RAFT) polymerization or as a monomer for producing functionalized polymers with tailored properties.
• Pharmaceutical Intermediates: A key building block in the synthesis of drug candidates and active pharmaceutical ingredients (APIs) that require specific thiol or alcohol functionalities.
• Ligand Synthesis for Catalysis: Used to prepare chelating ligands for metal catalysts, particularly in asymmetric synthesis and industrial chemical processes.
• Adhesive & Coating Formulations: Acts as an adhesion promoter or a reactive diluent in specialty epoxy, polyurethane, and silicone-based systems.

Basic Information

Product Name	6-Mercaptohexan-1-ol
CAS No.	1633-78-9
Molecular Formula	C6H14OS
Molecular Weight	134.24 g/mol
Synonyms	6-Mercapto-1-hexanol; 1-Hexanol, 6-mercapto-; 6-Hydroxyhexyl mercaptan; 6-Sulfanylhexan-1-ol; Hexane-1,6-dithiol (Note: This is a common misnomer; the correct name refers to the hydroxyl derivative); ω-Mercaptohexyl alcohol; 6-Thiohexanol; HS-(CH2)6-OH
EINECS	216-646-6

Quality Control

Our 6-Mercaptohexan-1-ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and volatility. Keep away from strong oxidizing agents, strong acids, and strong bases. Due to its hygroscopic and highly volatile nature, allow the container to reach ambient temperature before opening to prevent moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.