Description

2-Chloropropionitrile is a versatile chlorinated nitrile compound that serves as a key synthetic intermediate in organic chemistry. Its value lies in its bifunctional reactivity, where the nitrile group and the chlorine atom on the α-carbon can be selectively modified to construct more complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing various active pharmaceutical ingredients (APIs), particularly those containing β-amino nitrile or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the chloropropionitrile moiety is incorporated into the final molecule.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and cyanoethylation reactions to introduce the 2-chloropropionyl group into target compounds.
• Polymer & Resin Modifier: Acts as a precursor or cross-linking agent in the manufacture of specialty polymers, coatings, and adhesives.
• Chemical Research & Development: Serves as a valuable starting material in academic and industrial R&D labs for exploring new synthetic pathways and novel compounds.

Basic Information

Product Name	2-Chloropropionitrile
CAS No.	1617-17-0
Molecular Formula	C3H4ClN
Molecular Weight	89.52 g/mol
Synonyms	2-Chloropropanenitrile; α-Chloropropionitrile; Propionitrile, 2-chloro-; Chloropropionitrile; 2-Chloroethyl cyanide (less common); NSC 8815; α-Chloropropiononitrile
EINECS	216-574-5

Quality Control

Our 2-Chloropropionitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay by GC or HPLC, identity confirmation (IR), and control of key impurities and water content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	1.14 - 1.16 g/mL
Refractive Index (n20D)	1.435 - 1.445

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.