Description

1-(4-Fluorophenyl)But-1-En-3-One is a high-purity fluorinated organic building block characterized by its α,β-unsaturated ketone (enone) structure. This compound is a versatile intermediate prized for its reactivity, enabling the synthesis of more complex molecules in advanced research and manufacturing. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical R&D teams for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for organic electronic materials, liquid crystals, and advanced polymers due to its conjugated system.
• Chemical Research & Development: Employed in organic synthesis for Michael addition reactions, cyclization processes, and as a scaffold for heterocyclic compound formation.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing specific aromatic compounds, though typically in high-purity, research-grade quantities.

Basic Information

Product Name	1-(4-Fluorophenyl)But-1-En-3-One
CAS No.	1611-38-7
Molecular Formula	C₁₀H₉FO
Molecular Weight	164.18 g/mol
Synonyms	4'-Fluorochalcone; (E)-1-(4-Fluorophenyl)-3-buten-1-one; 3-Buten-1-one, 1-(4-fluorophenyl)-; 4-Fluorobenzylideneacetone; 1-(4-Fluorophenyl)-3-buten-1-one; p-Fluorochalcone; (E)-4'-Fluorochalcone; NSC 403697
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)But-1-En-3-One adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its properties, this material should be stored under an inert atmosphere to minimize oxidation and kept away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.