Description

2,2-Difluoro-1,3-Benzodioxole is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoro moiety, which is crucial for modulating the electronic and physical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the introduction of fluorine atoms into bioactive molecules, enhancing metabolic stability, lipophilicity, and membrane permeability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where fluorine substitution improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic cores that are essential for high-performance electronic display and lighting materials.
• Polymer & Resin Modification: Incorporated into polymer backbones to impart specific properties such as chemical resistance, thermal stability, or altered refractive index.
• Organic Synthesis Reagent: Employed in various coupling reactions and as a precursor for other complex fluorinated structures in academic and industrial research.
• Fluorine Chemistry Research: A valuable compound for studying the effects of gem-difluoro substitution on adjacent functional groups and reaction pathways.

Basic Information

Product Name	2,2-Difluoro-1,3-Benzodioxole
CAS No.	1583-59-1
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	2,2-Difluorobenzodioxole; 1,3-Benzodioxole, 2,2-difluoro-; 2,2-Difluoro-1,3-benzodioxolane; Difluorobenzodioxole; 2,2-Difluoro-1,3-benzodioxol; 2,2-Difluoro-benzo[1,3]dioxole; Benzo[1,3]dioxole, 2,2-difluoro-
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-1,3-Benzodioxole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and incompatible materials such as strong acids and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.