Description

Diethylisopropylphosphonate is a versatile organophosphorus compound widely used as a key synthetic intermediate. Its primary value lies in its role as a crucial building block for the preparation of complex phosphonates, phosphonic acids, and other phosphorus-containing molecules. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it facilitates the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with phosphonate-based bioisosteres or prodrug functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators that incorporate phosphonate or phosphonic acid groups.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized phosphine ligands and organometallic catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Flame Retardant Development: Acts as a reactive intermediate in the creation of organophosphorus flame retardants and plasticizers for polymers and resins.
• Extraction and Chelation Chemistry: Employed in the development of selective extractants and chelating agents for metal ion separation and recovery processes.
• Material Science Research: Utilized in the synthesis of functionalized surfaces, metal-organic frameworks (MOFs), and other advanced materials where phosphonate groups are required for binding or modification.

Basic Information

Product Name	Diethylisopropylphosphonate
CAS No.	1538-69-8
Molecular Formula	C7H17O3P
Molecular Weight	180.18 g/mol
Synonyms	Diethyl (1-methylethyl)phosphonate; Isopropylphosphonic Acid Diethyl Ester; Diethyl Isopropylphosphonate; (Isopropoxy)phosphonic Acid Diethyl Ester; Diethyl Isopropyl Phosphonate; Phosphonic Acid, (1-Methylethyl)-, Diethyl Ester; Diethyl (Isopropyl)phosphonate; Diethyl Isopropyl Phosphite (common misnomer)
EINECS	216-276-3

Quality Control

Our Diethylisopropylphosphonate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for manufacturing and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.425
Density (20°C)	1.010 - 1.030 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.