Description

2-Chloroethyl Fluoroacetate is a specialized fluorinated organic ester with significant utility as a key synthetic intermediate. Its value lies in its bifunctional reactivity, offering both a chloroethyl and a fluoroacetate moiety for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to introduce fluorine-containing groups into target molecules, thereby enhancing their biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom improves lipophilicity and target binding.
• Chemical Research & Development: Serves as a versatile reagent in organic synthesis for introducing fluoroacetate esters into complex molecules.
• Material Science Precursor: Potential use in the development of specialty polymers and surface-modifying agents with unique properties.
• Fluorine Chemistry Studies: Employed in academic and industrial labs to study reaction mechanisms and develop new fluorination methodologies.

Basic Information

Product Name	2-Chloroethyl Fluoroacetate
CAS No.	1537-62-8
Molecular Formula	C4H6ClFO2
Molecular Weight	140.54 g/mol
Synonyms	Fluoroacetic Acid 2-Chloroethyl Ester; 2-Chloroethyl Fluoroethanoate; Ethanol, 2-chloro-, fluoroacetate; 2-Chloroethanol Fluoroacetate; Chloroethyl Fluoroacetate; NSC 88425; Fluoroacetyl Chloride Ethylene Acetal (related compound); 1537-62-8
EINECS	Contact for details

Quality Control

Our 2-Chloroethyl Fluoroacetate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.