Description

Acetic Acid, 2,2,2-Trifluoro-, 1-Methylpropyl Ester is a specialized fluorinated organic ester, also known by its CAS number 1536-78-3. This compound is valued for its unique combination of being a highly volatile solvent with properties of a strong acid/organic solvent, making it a critical intermediate and reagent in advanced chemical synthesis. It is primarily sought after by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications requiring precise fluorination and esterification reactions.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoroacetyl or related fluorinated groups.
• Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, pesticides, and fungicides with enhanced activity and stability.
• Specialty Chemical Manufacturing: Acts as a versatile reagent and solvent in the production of fluorinated polymers, liquid crystals, and electronic chemicals.
• Laboratory Research & Development: Employed as a high-purity reagent for method development, catalysis studies, and exploratory organic synthesis in academic and industrial R&D settings.
• Chemical Derivatization Agent: Used in analytical chemistry for the derivatization of compounds to improve their detection in techniques like gas chromatography (GC) and mass spectrometry (MS).

Basic Information

Product Name	Acetic Acid, 2,2,2-Trifluoro-, 1-Methylpropyl Ester
CAS No.	1536-78-3
Molecular Formula	C7H11F3O2
Molecular Weight	184.16 g/mol
Synonyms	1-Methylpropyl 2,2,2-trifluoroacetate; sec-Butyl trifluoroacetate; Trifluoroacetic acid sec-butyl ester; 2-Butyl trifluoroacetate; Trifluoroacetic acid 1-methylpropyl ester; 2,2,2-Trifluoroacetic Acid Butyl Ester (sec); TFAA sec-Butyl Ester; Butan-2-yl 2,2,2-trifluoroacetate
EINECS	Contact for details

Quality Control

Our Acetic Acid, 2,2,2-Trifluoro-, 1-Methylpropyl Ester is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the exacting standards required for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.355 - 1.365
Density (g/mL at 20°C)	1.10 - 1.20
Related Substances (GC)	Report on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.