Description

1-[4-(2-Chloro-1,1,2-Trifluoro-Ethoxy)-Phenyl]-Ethanone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its core value lies in its unique molecular structure, which incorporates both a reactive acetyl group and a chloro-trifluoroethoxy moiety, making it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

This versatile fluorinated intermediate is designed for high-value synthesis applications, including:

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance and unique surface properties.
• Organic Synthesis & Catalysis Research: A valuable substrate for methodological development in cross-coupling reactions and fluorination chemistry.

Basic Information

Product Name	1-[4-(2-Chloro-1,1,2-Trifluoro-Ethoxy)-Phenyl]-Ethanone
CAS No.	1536-63-6
Molecular Formula	C10H8ClF3O2
Molecular Weight	252.62 g/mol
Synonyms	2-Chloro-1,1,2-trifluoroethyl 4-acetylphenyl ether; 4'-Acetyl-2-chloro-1,1,2-trifluoroethyl phenyl ether; 1-[4-(2-Chloro-1,1,2-trifluoroethoxy)phenyl]ethan-1-one; p-(2-Chloro-1,1,2-trifluoroethoxy)acetophenone; 4-Acetylphenyl 2-chloro-1,1,2-trifluoroethyl ether; 1536-63-6; CF3CFClCH2OC6H4COCH3
EINECS	Contact for details

Quality Control

Our 1-[4-(2-Chloro-1,1,2-Trifluoro-Ethoxy)-Phenyl]-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.