Description

Difluoromethyl Phenyl Sulfone is a versatile organosulfur compound featuring a difluoromethyl group attached to a phenyl sulfone moiety. This structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for introducing the difluoromethyl group, which can significantly alter the physicochemical and biological properties of target molecules. It is primarily sought after by pharmaceutical researchers and agrochemical developers for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a difluoromethyl motif for enhanced metabolic stability or bioavailability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the difluoromethyl group can improve efficacy.
• Material Science: Potential monomer or modifier in the development of specialty polymers with unique thermal or chemical resistance properties.
• Organic Synthesis Reagent: Serves as a difluoromethylating agent or electrophile in various cross-coupling and nucleophilic substitution reactions under controlled conditions.
• Ligand and Catalyst Development: Useful scaffold for creating novel ligands in coordination chemistry and catalysis research.
• Life Science Research: Employed as a biochemical tool compound in medicinal chemistry programs for probing structure-activity relationships (SAR).

Basic Information

Product Name	Difluoromethyl Phenyl Sulfone
CAS No.	1535-65-5
Molecular Formula	C7H6F2O2S
Molecular Weight	192.18 g/mol
Synonyms	α,α-Difluoromethyl Phenyl Sulfone; (Difluoromethyl)(phenyl) Sulfone; Benzenesulfonyl Difluoromethane; Phenylsulfonyl Difluoromethane; 1,1-Difluoro-1-(phenylsulfonyl)methane; DFMPS
EINECS	Contact for details

Quality Control

Our Difluoromethyl Phenyl Sulfone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. Standard quality parameters include assay (by HPLC), identity confirmation (IR, NMR), and control of key impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all test results against established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.