Description

3'-(Trifluoromethyl)Propiophenone CAS NO 1533-03-5 is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its value lies in the unique reactivity of the trifluoromethyl group and the carbonyl moiety, enabling the construction of complex molecular architectures. This intermediate is critically needed by pharmaceutical, agrochemical, and advanced materials research and development teams for creating novel active ingredients and functional compounds.

Application

• Key pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethylphenyl moiety for enhanced metabolic stability and bioavailability.
• Versatile building block in agrochemical research for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Precursor for ligand synthesis in catalysis and material science, contributing to the development of specialized catalysts.
• Used in organic electronic materials research for constructing fluorinated molecular components.
• Intermediate for fine chemical and flavor & fragrance compound synthesis where specific fluorination patterns are required.
• Starting material in academic and industrial R&D for methodological studies in fluoroorganic chemistry.

Basic Information

Product Name	3'-(Trifluoromethyl)Propiophenone
CAS No.	1533-03-5
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	1-Propanone, 1-[3-(trifluoromethyl)phenyl]-; 3'-Trifluoromethylpropiophenone; 3-(Trifluoromethyl)propiophenone; m-Trifluoromethylpropiophenone; 1-(3-Trifluoromethylphenyl)propan-1-one; 3-Trifluoromethyl-1-phenyl-1-propanone; Propiophenone, 3'-trifluoromethyl-; 3-TFM Propiophenone
EINECS	Contact for details

Quality Control

Our 3'-(Trifluoromethyl)Propiophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided and available upon request, supporting compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.