Description

1-Cyanopyrrolidine is a versatile heterocyclic nitrile building block, essential for advanced organic synthesis and pharmaceutical research. Its pyrrolidine ring and reactive cyano group make it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing pyrrolidine scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetic Research: Employed in medicinal chemistry for the design and synthesis of peptide analogs and protease inhibitors.
• Chemical Biology Probes: Useful building block for synthesizing molecular probes and tags used in biochemical and cellular studies.
• Material Science: Intermediate in the production of specialty polymers and functional materials with tailored properties.

Basic Information

Product Name	1-Cyanopyrrolidine
CAS No.	1530-88-7
Molecular Formula	C5H8N2
Molecular Weight	96.13 g/mol
Synonyms	Pyrrolidine-1-carbonitrile; 1-Pyrrolidinecarbonitrile; N-Cyanopyrrolidine; Pyrrolidin-1-yl cyanide; 1-Cyanoazolidine; NSC 5239; 1-Pyrrolidineacetonitrile (common misnomer)
EINECS	216-235-5

Quality Control

Our 1-Cyanopyrrolidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.