Description

6Beta-Fluoro-3Beta,5Alpha,17-Trihydroxy-16Alpha-Methylpregnan-20-One 3-Acetate is a high-purity synthetic steroid derivative, serving as a critical pharmaceutical intermediate. Its value lies in its specific fluorinated and hydroxylated structure, which is essential for the synthesis of advanced corticosteroid and other steroidal active pharmaceutical ingredients (APIs). This compound is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract development and manufacturing organizations (CDMOs) engaged in the production of specialized steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent glucocorticoid and anti-inflammatory steroid APIs.
• Research & Development: Used in medicinal chemistry for the development and structural modification of new steroidal drug candidates.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of steroid-based drugs.
• Biochemical Research: Utilized in studies investigating steroid hormone receptor interactions and metabolic pathways.

Basic Information

Product Name	6Beta-Fluoro-3Beta,5Alpha,17-Trihydroxy-16Alpha-Methylpregnan-20-One 3-Acetate
CAS No.	1525-77-5
Molecular Formula	C24H37FO5
Molecular Weight	424.55 g/mol
Synonyms	6β-Fluoro-3β,5α,17-trihydroxy-16α-methylpregnan-20-one 3-acetate; 16α-Methyl-6β-fluoro-3β,5α,17-trihydroxypregnan-20-one 3-acetate; Fluocortolone 3-Acetate Intermediate; 6β-Fluorotriamcinolone 16,17-acetonide related compound; (3β,5α,6β,16α)-6-Fluoro-3,5,17-trihydroxy-16-methylpregnan-20-one 3-acetate
EINECS	Contact for details

Quality Control

Our 6Beta-Fluoro-3Beta,5Alpha,17-Trihydroxy-16Alpha-Methylpregnan-20-One 3-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.