Description

3-Chloro-4-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the toluene ring, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is essential for manufacturers and R&D teams in the pharmaceutical and agrochemical sectors seeking to develop novel active ingredients with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted toluene core.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides, where the halogen atoms contribute to biological activity.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Employed in the research and development of organic semiconductors and electro-optical materials.
• Chemical Research & Development: A valuable reagent for cross-coupling reactions (e.g., Suzuki, Negishi) and other functional group transformations in medicinal and process chemistry.
• Dye and Pigment Intermediates: Used in the synthesis of specialized halogenated dyes and pigments.

Basic Information

Product Name	3-Chloro-4-Fluorotoluene
CAS No.	1513-25-3
Molecular Formula	C7H6ClF
Molecular Weight	144.57 g/mol
Synonyms	1-Chloro-2-fluoro-4-methylbenzene; 3-Chloro-4-fluoromethylbenzene; 4-Fluoro-3-chlorotoluene; 2-Fluoro-5-chlorotoluene; Toluene, 3-chloro-4-fluoro-; 3-Chloro-4-fluoro-1-methylbenzene; 4-Methyl-2-fluorochlorobenzene; Benzene, 1-chloro-2-fluoro-4-methyl-
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and strong oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Density (20°C)	~1.20 g/cm³
Boiling Point	~185-190 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.