Description

Diethyl 2-Acetylglutarate is a high-purity diester compound with significant utility as a versatile chemical intermediate. Its bifunctional structure, featuring both ester and ketone groups, makes it a valuable building block for synthesizing more complex molecules. This product is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key starting material or building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex cyclic or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where its reactive sites allow for structural diversification.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty organic compounds requiring specific ester and ketone functionalities.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent in the development of specialty polymers and resins with tailored properties.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex molecular architectures via reactions like Michael additions, condensations, and cyclizations.
• Chemical Intermediate for Dyes & Pigments: Employed in the synthesis of organic colorants and advanced photoactive materials.

Basic Information

Product Name	Diethyl 2-Acetylglutarate
CAS No.	1501-06-0
Molecular Formula	C11H18O5
Molecular Weight	230.26 g/mol
Synonyms	2-Acetylpentanedioic Acid Diethyl Ester; Diethyl α-Acetylglutarate; Ethyl 2-Acetylglutarate; Glutaric Acid, 2-Acetyl-, Diethyl Ester; 1,5-Diethyl 2-Acetylpentanedioate; Acetylglutaric Acid Diethyl Ester; 1501-06-0; Diethyl (acetyl)glutarate
EINECS	216-110-8

Quality Control

Our Diethyl 2-Acetylglutarate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.430 - 1.440
Density (20°C)	1.070 - 1.090 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.