Description

1-(4-Ethyl-Phenyl)-4,4,4-Trifluoro-Butane-1,3-Dione is a specialized fluorinated diketone compound, serving as a high-value building block in advanced organic synthesis. Its core value lies in the trifluoromethyl and β-diketone functional groups, which are pivotal for modulating the physical, chemical, and biological properties of target molecules. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and materials science industries seeking to introduce fluorine for enhanced metabolic stability, lipophilicity, and electronic effects.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic or heterocyclic motifs to improve drug-like properties.
• Agrochemical Synthesis: Used in developing novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a chelating agent or precursor for metal-organic frameworks (MOFs) and catalysts in asymmetric synthesis.
• Advanced Material Research: Building block for fluorinated polymers, liquid crystals, and organic electronic materials to tune solubility and optoelectronic characteristics.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and creating complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	1-(4-Ethyl-Phenyl)-4,4,4-Trifluoro-Butane-1,3-Dione
CAS No.	1495-03-0
Molecular Formula	C12H11F3O2
Molecular Weight	244.21 g/mol
Synonyms	4'-Ethyl-2,2,2-trifluoroacetophenone; 1-(4-Ethylphenyl)-4,4,4-trifluorobutane-1,3-dione; 4-Ethylphenyl trifluoroacetyl methane; p-Ethylphenyl trifluoroacetyl methane; 4,4,4-Trifluoro-1-(4-ethylphenyl)-1,3-butanedione; 1495-03-0; 1-(4-Ethylphenyl)-4,4,4-trifluoro-1,3-butanedione
EINECS	Contact for details

Quality Control

Our 1-(4-Ethyl-Phenyl)-4,4,4-Trifluoro-Butane-1,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.