Description

Trifluoromethanol is a highly volatile organofluorine compound with the molecular formula CHF3O. This specialty fluorinated building block is valued for its unique reactivity, serving as a key intermediate in the synthesis of advanced materials and pharmaceuticals. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced material science sectors for introducing the trifluoromethoxy group, a moiety known to enhance metabolic stability and lipophilicity in target molecules.

Application

• Pharmaceutical Intermediate: Critical for synthesizing active pharmaceutical ingredients (APIs) containing the trifluoromethoxy (OCF3) group to improve drug potency and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group contributes to enhanced biological activity and environmental profile.
• Fluorinated Polymer Research: Serves as a monomer or modifier in the development of specialty polymers with unique surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Building Block: Employed in laboratories for the preparation of complex fluorinated organic compounds for material science and chemical research.
• Liquid Crystal & Electronic Material Development: Used in the synthesis of fluorinated components for liquid crystal displays (LCDs) and dielectric materials.

Basic Information

Product Name	Trifluoromethanol
CAS No.	1493-11-4
Molecular Formula	CHF3O
Molecular Weight	86.02 g/mol
Synonyms	Methanol, trifluoro-; Trifluoromethyl alcohol; Fluoroform, hydroxy-; Trifluoro carbinol; OCF3H; Hydroxytrifluoromethane; Perfluoromethanol; Trifluoromethoxy precursor
EINECS	Contact for details

Quality Control

Our Trifluoromethanol is produced and handled under stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including Gas Chromatography (GC) and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature and sensitivity to strong bases, store in a cool, well-ventilated area, away from heat and incompatible materials such as strong alkalis. For long-term stability, storage under an inert atmosphere (e.g., nitrogen or argon) in a dedicated, temperature-controlled environment (recommended 2-8°C) is advised.

Specification

Item	Specification
Appearance	Colorless liquid / gas
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acidity (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.