Description

4'-Fluoro-2'-Hydroxyacetophenone is a versatile fluorinated aromatic ketone and a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic combination of a reactive acetyl group with fluorine and hydroxyl substituents, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing fluorinated drug candidates, including potential anti-inflammatory, antibacterial, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated organic molecules used in electronic displays and optoelectronic devices.
• Fine Chemical & Dye Intermediate: Employed in the synthesis of complex fluorinated dyes, pigments, and specialty fine chemicals.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, particularly in cross-coupling and fluorination chemistry.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4'-Fluoro-2'-Hydroxyacetophenone
CAS No.	1481-27-2
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	1-(2-Hydroxy-4-fluorophenyl)ethanone; 2'-Hydroxy-4'-fluoroacetophenone; 4-Fluoro-2-hydroxyacetophenone; 2-Acetyl-5-fluorophenol; 4-Fluoro-2-hydroxyphenyl methyl ketone; 1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 4'-Fluro-2'-Hydroxyacetophenone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.