Description

18-β-Glycyrrhetinic Acid Methyl Ester is a high-purity, semi-synthetic derivative of glycyrrhetinic acid, a key bioactive triterpenoid from licorice root. This compound is valued for its enhanced bioavailability and potent biological activity compared to its parent acid, making it a critical intermediate for advanced research and pharmaceutical development. It is primarily sought by manufacturers in the pharmaceutical, cosmetic, and nutraceutical industries for developing anti-inflammatory, antiviral, and skin-care formulations.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of more potent anti-inflammatory and hepatoprotective drugs.
• Cosmetic & Skincare Actives: Used in formulations for its soothing, anti-redness, and skin-brightening properties.
• Research & Development: Serves as a standard or reference compound in pharmacological and biochemical studies targeting specific enzymes and pathways.
• Nutraceutical Ingredients: Incorporated into dietary supplements for its potential health-supporting benefits.
• Veterinary Medicine: Employed in the development of treatments for animal inflammatory conditions.

Basic Information

Product Name	18-β-Glycyrrhetinic Acid Methyl Ester
CAS No.	1477-44-7
Molecular Formula	C₃₂H₅₀O₄
Molecular Weight	514.74 g/mol
Synonyms	Methyl Glycyrrhetinate; Methyl 18β-Glycyrrhetinate; Enoxolone Methyl Ester; Methyl 3β-Hydroxy-11-oxoolean-12-en-30-oate; (18β)-3β-Hydroxy-11-oxoolean-12-en-30-oic Acid Methyl Ester; Methyl 18β-Glycyrrhetinic Acid; 18β-Glycyrrhetinic Acid Methyl Ester; Licorice Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 18-β-Glycyrrhetinic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical and cosmetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.