Description

1-Phenylcyclobutanecarbaldehyde is a versatile aromatic aldehyde building block characterized by its unique cyclobutane ring fused to a phenyl group. This compound matters as a key chiral intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drug candidates.
• Chiral Synthesis: Serves as a starting material or intermediate for the preparation of enantiomerically pure compounds, leveraging the stereogenic center of the cyclobutane ring.
• Ligand and Catalyst Development: Used in the research and development of novel ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Agrochemical Intermediates: Acts as a building block for the development of novel crop protection agents and herbicides.
• Flavor and Fragrance Chemistry: Utilized in the research and synthesis of novel aromatic compounds for specialty applications.

Basic Information

Product Name	1-Phenylcyclobutanecarbaldehyde
CAS No.	1469-83-6
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	1-Phenylcyclobutanecarboxaldehyde; 1-Phenylcyclobutane-1-carbaldehyde; Cyclobutyl(phenyl)methanal; 1-Phenyl-1-cyclobutanecarboxaldehyde; 1-Phenylcyclobutylcarboxaldehyde; (1-Phenylcyclobutyl)methanal; 1-Phenylcyclobutane-1-carboxaldehyde; 1-Phenylcyclobutanecarbonal
EINECS	Contact for details

Quality Control

Our 1-Phenylcyclobutanecarbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.