Description

trans-4-Henylcyclohexanecarboxylic Acid is a high-purity, versatile organic acid derivative characterized by its rigid cyclohexane backbone substituted with a carboxylic acid group and a phenyl ring. This compound is a critical chiral building block and intermediate in advanced organic synthesis, valued for its ability to impart specific stereochemistry and structural properties to target molecules. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular architecture is paramount for functionality.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Liquid Crystal Materials: Serves as a core component in the synthesis of advanced liquid crystal compounds used in display technologies (LCDs).
• Agrochemical Synthesis: Intermediate in the production of novel herbicides and plant growth regulators with enhanced efficacy.
• Polymer Modification: Used to introduce cyclohexyl-phenyl motifs into polymer chains, improving thermal stability and mechanical properties of engineering plastics.
• Organic Light-Emitting Diodes (OLEDs): Building block for electron-transport or host materials in OLED device fabrication.
• Asymmetric Catalysis: Employed as a precursor for chiral ligands or catalysts in enantioselective synthesis.
• Cosmetic & Personal Care Ingredients: Intermediate for UV absorbers or stabilizers in high-performance sunscreen formulations.
• Academic & Industrial R&D: A valuable standard and reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	trans-4-Henylcyclohexanecarboxylic Acid
CAS No.	1466-73-5
Molecular Formula	C14H18O2
Molecular Weight	218.29 g/mol
Synonyms	trans-4-Phenylcyclohexanecarboxylic Acid; (1r,4r)-4-Phenylcyclohexanecarboxylic Acid; 4-Phenylcyclohexanecarboxylic Acid, trans-; 4-PCCA; 4-Phenyl-1-cyclohexanecarboxylic Acid; 4-Carboxyphenylcyclohexane; 4-Phenylcyclohexane-1-carboxylic Acid; 4-PCHA
EINECS	Contact for details

Quality Control

Our trans-4-Henylcyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for sensitive pharmaceutical and electronic material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isomeric Purity (trans-)	≥ 99.0%
Melting Point	165 - 170 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.