Description

Ethyl 2-Chloronicotinate is a versatile chlorinated nicotinate ester, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value proposition lies in enabling the efficient construction of complex heterocyclic scaffolds, particularly within the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists in fine chemical, pharmaceutical, and crop protection industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, including kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and fungicides that require functionalized pyridine cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Utilized in methodological research and the discovery of new synthetic pathways in organic chemistry.

Basic Information

Product Name	Ethyl 2-Chloronicotinate
CAS No.	1452-94-4
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	2-Chloronicotinic Acid Ethyl Ester; Ethyl 2-Chloro-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid, 2-chloro-, ethyl ester; 2-Chloro-3-ethoxycarbonylpyridine; 2-Chloropyridine-3-carboxylic Acid Ethyl Ester; NSC 404087; AI3-52090
EINECS	215-915-7

Quality Control

Our Ethyl 2-Chloronicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.