Description

5-Bromo-2-Hydroxyacetophenone is a versatile brominated aromatic ketone that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a reactive acetylphenol moiety, makes it a valuable building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators due to its bioactive phenolic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoresponsive polymers.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing brominated azo dyes and high-performance pigments.
• Academic and R&D: Fundamental reagent in university and corporate research laboratories for methodological studies and exploring new chemical reactions.

Basic Information

Product Name	5-Bromo-2-Hydroxyacetophenone
CAS No.	1450-75-5
Molecular Formula	C8H7BrO2
Molecular Weight	215.05 g/mol
Synonyms	1-(5-Bromo-2-hydroxyphenyl)ethanone; 2'-Hydroxy-5'-bromoacetophenone; 5-Bromo-2'-hydroxyacetophenone; 5-Bromo-2-acetylphenol; 2-Acetyl-4-bromophenol; 4-Bromo-2-hydroxyacetophenone; 5-Bromosalicylophenone
EINECS	215-909-4

Quality Control

Our 5-Bromo-2-Hydroxyacetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.