Description

18Alpha-Glycyrrhetinic Acid is a pentacyclic triterpenoid derivative and a primary bioactive component of licorice root (Glycyrrhiza glabra). This compound is highly valued for its potent anti-inflammatory, antiviral, and hepatoprotective properties, making it a critical intermediate for advanced pharmaceutical and cosmetic formulations. It is essential for manufacturers in the pharmaceutical, nutraceutical, and personal care industries seeking to develop products with targeted therapeutic and skin-enhancing effects.

Application

• Pharmaceutical Intermediates: A key starting material for the synthesis of potent anti-inflammatory drugs, hepatoprotective agents, and antiviral medications.
• Cosmetic & Skincare Actives: Incorporated into creams, serums, and lotions for its skin-soothing, anti-redness, and anti-aging benefits, often to treat conditions like eczema and psoriasis.
• Nutraceuticals & Dietary Supplements: Used in formulations aimed at supporting liver health, reducing gastric discomfort, and providing systemic anti-inflammatory support.
• Research & Development: Serves as a reference standard and a crucial compound in biochemical and pharmacological research for studying triterpenoid pathways and biological activities.
• Oral Care Products: Utilized in toothpaste and mouthwash for its anti-inflammatory and antimicrobial properties to promote gum health.
• Veterinary Pharmaceuticals: Applied in topical and systemic treatments for animals to address inflammation and support dermal health.

Basic Information

Product Name	18Alpha-Glycyrrhetinic Acid
CAS No.	1449-05-4
Molecular Formula	C30H46O4
Molecular Weight	470.68 g/mol
Synonyms	18α-Glycyrrhetinic Acid; (18α)-Glycyrrhetinic Acid; Enoxolone; 18α-GA; Glycyrrhetin; Uralenic Acid; 3β-Hydroxy-11-oxoolean-12-en-30-oic Acid; Glycyrrhetic Acid
EINECS	215-889-5

Quality Control

Our 18Alpha-Glycyrrhetinic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.