Description

2-Chloroquinoxaline is a versatile halogenated heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its reactive chlorine atom and the quinoxaline scaffold, enabling the construction of complex molecules with tailored properties. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various biologically active quinoxaline derivatives, including potential anticancer, antimicrobial, and antiviral agents.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides that leverage the quinoxaline structure for enhanced efficacy.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Dye and Pigment Chemistry: Acts as an intermediate in the production of specialized dyes and pigments due to the chromophoric quinoxaline core.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination to introduce diverse functional groups.
• Ligand Preparation: Utilized for synthesizing complexing agents and chelating ligands used in catalysis and metal ion sensing.

Basic Information

Product Name	2-Chloroquinoxaline
CAS No.	1448-87-9
Molecular Formula	C8H5ClN2
Molecular Weight	164.59 g/mol
Synonyms	Quinoxaline, 2-chloro-; 2-Chloro-quinoxaline; 2-Chloroquinoxaline; Quinoxalin-2-yl chloride; 2-Chlorobenzopyrazine; NSC 5111; 1448-87-9
EINECS	215-904-8

Quality Control

Our 2-Chloroquinoxaline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for production, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.