Description

4-Acetylbenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a ketone and a nitrile group, makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical intermediates. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking reliable and consistent raw materials for their development and production processes.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing benzimidazole, quinazoline, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its aromatic core provides structural stability and functionality.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers due to its conjugated system and polar functional groups.
• Fine Chemical Production: Acts as a versatile synthon for manufacturing dyes, pigments, and other specialty chemicals requiring a para-substituted benzonitrile structure.

Basic Information

Product Name	4-Acetylbenzonitrile
CAS No.	1443-80-7
Molecular Formula	C9H7NO
Molecular Weight	145.16 g/mol
Synonyms	p-Acetylbenzonitrile; 4'-Cyanacetophenone; 4-Cyanophenyl methyl ketone; 1-(4-Cyanophenyl)ethanone; p-Cyanacetophenone; Methyl 4-cyanophenyl ketone; 4-Acetylbenzenecarbonitrile; p-Acetylphenyl cyanide
EINECS	215-889-4

Quality Control

Our 4-Acetylbenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support compliance with global regulatory standards including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	96 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.