Description

Acetic Acid 5-Chloro-6β-Nitro-5α-Cholestan-3β-Yl Ester is a specialized steroidal derivative, a key intermediate in the synthesis of complex bioactive molecules. Its unique structure, featuring chloro and nitro substituents on the cholestane backbone, makes it a valuable building block for pharmaceutical research and development. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or a synthetic starting material in academic and industrial research exploring steroid hormone pathways and receptor interactions.
• Chemical Synthesis: Serves as a versatile chiral building block for constructing more complex molecular architectures in medicinal chemistry.
• Metabolite Studies: Potential use in the synthesis of labeled analogs for pharmacokinetic, metabolic, and tracer studies.

Basic Information

Product Name	Acetic Acid 5-Chloro-6β-Nitro-5α-Cholestan-3β-Yl Ester
CAS No.	1431-22-7
Molecular Formula	C₂₉H₄₈ClNO₄
Molecular Weight	510.16 g/mol
Synonyms	5α-Cholestan-3β-yl 5-chloro-6-nitroacetate; 3β-Acetoxy-5α-chloro-6-nitrocholestane; 5-Chloro-6-nitro-5α-cholestan-3β-yl acetate; 5α-Chloro-6-nitrocholestan-3β-yl acetate; Cholestane-3β-yl 5-chloro-6-nitroacetate; (3β)-5-Chloro-6-nitrocholestan-3-yl acetate; 1431-22-7
EINECS	Contact for details

Quality Control

Our Acetic Acid 5-Chloro-6β-Nitro-5α-Cholestan-3β-Yl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.