Description

2-Bromo-4-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents on a toluene backbone, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the bromo and fluoro groups contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, enhancing electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and creating novel fluorinated compounds.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where halogen atoms modify color and fastness properties.

Basic Information

Item	Details
Product Name	2-Bromo-4-Fluorotoluene
CAS No.	1422-53-3
Molecular Formula	C7H6BrF
Molecular Weight	189.03 g/mol
Synonyms	1-Bromo-2-fluoro-4-methylbenzene; 2-Fluoro-4-methylbromobenzene; 4-Fluoro-2-bromotoluene; 2-Bromo-4-methylfluorobenzene; 4-Methyl-2-bromofluorobenzene; o-Bromo-p-fluorotoluene; Toluene, 2-bromo-4-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorotoluene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Density (20°C)	~1.55 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.