Description

(1S,8Aα)-1,4Aβ-Dimethyl-5β-(3-Methyl-2,4-Pentadienyl)-6-Methylenedecalin-1β-Carboxylic Acid Methyl Ester is a complex, high-purity diterpenoid ester derivative with significant value in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral intermediate or building block for the development of novel bioactive molecules. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for use in process chemistry, medicinal chemistry, and the synthesis of natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates and complex natural product derivatives.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route development for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Intermediate in the research and development of new pesticides or plant growth regulators with complex stereochemistry.
• Fine Chemical Synthesis: Valuable precursor for creating specialty chemicals, flavors, fragrances, or advanced materials requiring specific stereochemical configurations.
• Academic & Institutional Research: Used in universities and research institutes for studies in organic synthesis, catalysis, and chemical biology.

Basic Information

Product Name	(1S,8Aα)-1,4Aβ-Dimethyl-5β-(3-Methyl-2,4-Pentadienyl)-6-Methylenedecalin-1β-Carboxylic Acid Methyl Ester
CAS No.	1235-39-8
Molecular Formula	C₂₂H₃₂O₂
Molecular Weight	328.49 g/mol
Synonyms	Methyl (1S,4aR,5R,8aS)-5-[(2E)-4-Methylpenta-2,4-dien-1-yl]-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylate; Methyl Abietate Derivative; Abietic Acid Methyl Ester Derivative; (1S,4aR,5R,8aS)-5-[(2E)-4-Methyl-2,4-pentadien-1-yl]-1,4a-dimethyl-6-methylene-decahydronaphthalene-1-carboxylic Acid Methyl Ester; Rosin Acid Methyl Ester Derivative; Diterpene Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (1S,8Aα)-1,4Aβ-Dimethyl-5β-(3-Methyl-2,4-Pentadienyl)-6-Methylenedecalin-1β-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure high consistency and reliability for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and should be handled under inert conditions if prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Research Grade)
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.