Description

1-(5-Chloro-2-Hydroxyphenyl)-3-(4-Methoxyphenyl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative with significant commercial and research utility. This compound serves as a versatile pharmaceutical intermediate and a key building block in organic synthesis. It is primarily required by manufacturers and R&D facilities in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates with potential anti-inflammatory, antimicrobial, or anticancer activity.
• Agrochemical Research: Used as a lead compound or intermediate for developing new pesticides and herbicides, leveraging its chalcone scaffold.
• Organic Synthesis Building Block: Serves as a versatile starting material for synthesizing more complex heterocyclic compounds like flavones and pyrazolines.
• Material Science Research: Investigated for its potential application in creating organic light-emitting diodes (OLEDs) or non-linear optical (NLO) materials due to its conjugated structure.
• Biochemical Research: Employed in biochemical assays and as a standard or probe for studying enzyme inhibition or biological pathways.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and pigments where its specific molecular architecture is required.

Basic Information

Product Name	1-(5-Chloro-2-Hydroxyphenyl)-3-(4-Methoxyphenyl)Prop-2-En-1-One
CAS No.	1226-09-1
Molecular Formula	C16H13ClO3
Molecular Weight	288.73 g/mol
Synonyms	2'-Hydroxy-5'-chlorochalcone 4'-Methyl Ether; (E)-1-(5-Chloro-2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one; 5-Chloro-2-hydroxy-4'-methoxychalcone; 3-(4-Methoxyphenyl)-1-(5-chloro-2-hydroxyphenyl)-2-propen-1-one; NSC 403689; 1-(5-Chloro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; 4-Methoxy-3'-chlorochalcone
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-2-Hydroxyphenyl)-3-(4-Methoxyphenyl)Prop-2-En-1-One is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material is suitable for demanding GMP-grade pharmaceutical synthesis and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, extended exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.