Description

4-Phenyltetrahydro-2H-Pyran-4-Carbonitrile CAS NO 1202-81-9 is a versatile heterocyclic nitrile compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a phenyl-substituted tetrahydropyran ring fused with a nitrile group, makes it a valuable precursor for pharmaceuticals and fine chemicals. This intermediate is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers and specialty polymers with tailored thermal or optical properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors for biochemical research.
• Fine Chemical Production: Acts as a starting material for synthesizing complex fragrance and flavor compounds.

Basic Information

Product Name	4-Phenyltetrahydro-2H-Pyran-4-Carbonitrile
CAS No.	1202-81-9
Molecular Formula	C₁₂H₁₃NO
Molecular Weight	187.24 g/mol
Synonyms	4-Phenyltetrahydro-2H-pyran-4-carbonitrile; 4-Cyano-4-phenyltetrahydropyran; 4-Phenyl-4-cyanotetrahydropyran; 4-Phenyltetrahydropyran-4-carbonitrile; Tetrahydro-4-phenyl-2H-pyran-4-carbonitrile; 4-Phenyl-4-cyanooxane; 4-Phenyl-4-cyanotetrahydro-2H-pyran; 1202-81-9
EINECS	Contact for details

Quality Control

Our 4-Phenyltetrahydro-2H-Pyran-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.