Description

Methyl 4-Chloro-1H-Pyrrole-2-Carboxylate is a versatile heterocyclic building block, specifically a halogenated pyrrole ester, essential for advanced organic synthesis. Its core value lies in providing a reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those with pyrrole-based cores, such as kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the chlorinated pyrrole moiety can impart specific biological activity.
• Material Science Research: Serves as a monomer or building block for developing novel polymers, dyes, and organic electronic materials with unique optoelectronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in heterocyclic chemistry and medicinal chemistry programs.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty additives where precise molecular architecture is required.

Basic Information

Product Name	Methyl 4-Chloro-1H-Pyrrole-2-Carboxylate
CAS No.	1194-96-3
Molecular Formula	C6H6ClNO2
Molecular Weight	159.57 g/mol
Synonyms	Methyl 4-chloro-1H-pyrrole-2-carboxylate; 4-Chloro-1H-pyrrole-2-carboxylic acid methyl ester; Methyl 4-chloropyrrole-2-carboxylate; 2-Carbomethoxy-4-chloropyrrole; 4-Chloro-2-(methoxycarbonyl)-1H-pyrrole; 1H-Pyrrole-2-carboxylic acid, 4-chloro-, methyl ester
EINECS	214-798-9

Quality Control

Our production of Methyl 4-Chloro-1H-Pyrrole-2-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance in cGMP-aligned supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.