Description

(2R,3R)-2,3-Dibromo-5α-Cholestane CAS NO 1175-09-3 is a high-purity, stereochemically defined brominated sterane derivative, serving as a critical chiral intermediate and reference standard in advanced organic synthesis. Its precise stereochemistry and defined structure make it invaluable for research and development in complex molecule construction. This compound is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on steroid chemistry, asymmetric synthesis, and the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Chemical Research: Used as a model compound in studies of stereoselective bromination reactions, reaction mechanisms, and conformational analysis of steroidal systems.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in chromatographic (HPLC, GC) and spectroscopic analyses.
• Academic & Discovery Chemistry: Employed in university and institutional labs for exploring new synthetic pathways and training in advanced organic synthesis techniques.
• Material Science Precursor: Potential starting material for the synthesis of specialized liquid crystals or other functional organic materials with defined stereochemistry.

Basic Information

Item	Detail
Product Name	(2R,3R)-2,3-Dibromo-5α-Cholestane
CAS No.	1175-09-3
Molecular Formula	C27H46Br2
Molecular Weight	530.47 g/mol
Synonyms	5α-Cholestane-2β,3β-diol dibromide; 2β,3β-Dibromo-5α-cholestane; (2β,3β)-Dibromocholestane; Cholestane-2,3-diol dibromide; 2,3-Dibromocholestane; 1175-09-3; NSC 61739
EINECS	Contact for details

Quality Control

Our (2R,3R)-2,3-Dibromo-5α-Cholestane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and optical rotation to verify stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.