Description

Andrographin CAS NO 1165-40-8 is a bioactive labdane diterpenoid compound, a key secondary metabolite derived from the medicinal plant *Andrographis paniculata*. This high-purity phytochemical is valued for its significant role in research and development within the pharmaceutical and nutraceutical sectors. It serves as a critical reference standard and active ingredient for scientists and manufacturers focused on natural product-based solutions. Target industries include pharmaceutical R&D, dietary supplement formulation, and advanced botanical extract production.

Application

• Pharmaceutical Research: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in drug discovery programs.
• Nutraceutical & Dietary Supplements: Incorporated into formulations for immune support and general wellness products, leveraging its natural origin.
• Botanical Extract Standardization: Serves as a marker compound for the quality control and standardization of *Andrographis paniculata* extracts.
• Biochemical & Pharmacological Studies: Utilized in *in-vitro* and *in-vivo* studies to investigate anti-inflammatory, hepatoprotective, and other mechanistic pathways.
• Cosmeceuticals: Potential application in topical formulations for skin health due to its bioactive properties.
• Academic Research: A key compound for studies in phytochemistry, natural product isolation, and analytical method development.

Basic Information

Product Name	Andrographin
CAS No.	1165-40-8
Molecular Formula	C₂₀H₃₀O₅
Molecular Weight	350.45 g/mol
Synonyms	Andrographin; 3,19-Dihydroxy-ent-labda-8(17),13-dien-16,15-olide; 15,16-Epoxy-3,19-dihydroxy-ent-labda-8(17),13(16),14-trien-20,12-olide; Andrographolide derivative; 8(17),13-Labdadien-15,16-olide-3,19-diol; 3,19-Dihydroxy-labda-8(17),13-dien-16,15-olide; 15,16-Epoxy-3β,19-dihydroxy-labda-8(17),13(16),14-trien-20,12-olide
EINECS	Contact for details

Quality Control

Our Andrographin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substance analysis, to meet rigorous pharmaceutical and research-grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurities are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.