Description

4-(4-Acetyl-3-Iodophenoxy)-3,5-Diiodobenzoic Acid is a high-purity, multi-iodinated aromatic compound that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique structure, featuring multiple iodine atoms and a carboxylic acid group, makes it a versatile precursor for constructing complex molecules, particularly in pharmaceutical research and material science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise, high-quality intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting thyroid hormone analogs, X-ray contrast agents, and other iodine-containing therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators where the iodine atoms and phenolic ether structure can impart specific biological activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers, liquid crystals, and organic electronic materials due to its rigid, multi-halogenated structure.
• Chemical Synthesis Reagent: Employed in organic synthesis for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions, where the iodine atoms act as excellent leaving groups.
• Radiopharmaceutical Labeling: Potential use as a precursor for compounds where radioactive iodine isotopes (I-123, I-125, I-131) can be incorporated for diagnostic or therapeutic applications.
• Research & Development: A valuable tool in academic and industrial R&D labs for exploring new chemical reactions and creating libraries of complex aromatic compounds.

Basic Information

Product Name	4-(4-Acetyl-3-Iodophenoxy)-3,5-Diiodobenzoic Acid
CAS No.	1160-36-7
Molecular Formula	C15H8I3O4
Molecular Weight	649.94 g/mol
Synonyms	3,5-Diiodo-4-(4-acetyl-3-iodophenoxy)benzoic Acid; Benzoic acid, 3,5-diiodo-4-[(4-acetyl-3-iodophenyl)oxy]-; 4-(4-Acetyl-3-iodophenoxy)-3,5-diiodobenzoic acid; 3,5-Diiodo-4-(4'-acetyl-3'-iodophenoxy)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-(4-Acetyl-3-Iodophenoxy)-3,5-Diiodobenzoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, for comprehensive characterization and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and compliance with customer specifications. Our quality management system is designed to meet the rigorous standards required for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store this material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.