Description

5-Methyl-3-Phenylisoxazole-4-Carboxylic Acid is a versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a key intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those with isoxazole core structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Organic Synthesis Building Block: Employed in medicinal chemistry and material science for constructing complex heterocyclic compounds via reactions like amidation, esterification, and cyclization.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial laboratories for method development and novel compound library synthesis.
• Coordination Chemistry: The carboxylic acid group can act as a ligand for metal ions, useful in creating catalysts or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Methyl-3-Phenylisoxazole-4-Carboxylic Acid
CAS No.	1136-45-4
Molecular Formula	C11H9NO3
Molecular Weight	203.19 g/mol
Synonyms	5-Methyl-3-phenyl-4-isoxazolecarboxylic acid; 4-Isoxazolecarboxylic acid, 5-methyl-3-phenyl-; 3-Phenyl-5-methylisoxazole-4-carboxylic acid; 5-Methyl-3-phenyl-1,2-oxazole-4-carboxylic acid; NSC 403697; 1136-45-4; 5-Methyl-3-phenyl-4-carboxyisoxazole
EINECS	214-515-6

Quality Control

Our production of 5-Methyl-3-Phenylisoxazole-4-Carboxylic Acid adheres to stringent in-process controls and final batch testing to ensure consistent high purity and reliable performance. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We are committed to meeting the exacting standards required for pharmaceutical and agrochemical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.