Description

4-Chloro-5,6,7,8-Tetrahydro-Quinazoline is a versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a key intermediate for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, especially those targeting central nervous system (CNS) disorders and kinase inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinazoline scaffold's bioactivity.
• Ligand & Catalyst Development: Serves as a building block for creating novel ligands in coordination chemistry and catalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-5,6,7,8-Tetrahydro-Quinazoline
CAS No.	1125-62-8
Molecular Formula	C8H9ClN2
Molecular Weight	168.62 g/mol
Synonyms	4-Chloro-5,6,7,8-tetrahydroquinazoline; 5,6,7,8-Tetrahydro-4-chloroquinazoline; 4-Chlorotetrahydroquinazoline; Quinazoline, 4-chloro-5,6,7,8-tetrahydro-; 4-Chloro-5,6,7,8-tetrahydro-quinazoline; 1125-62-8 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Chloro-5,6,7,8-Tetrahydro-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.