Description

Cyclobutyl Chloride is a versatile organic halide building block essential for advanced chemical synthesis. Its strained four-membered ring structure makes it a valuable intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is particularly sought after by R&D chemists and process development scientists for introducing the cyclobutyl moiety, a key pharmacophore in modern drug discovery. The product is supplied with a guaranteed CAS number of 1120-57-6 for precise identification and regulatory compliance.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) containing the cyclobutyl ring, a structure found in various therapeutic agents.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the cyclobutyl group enhances biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialized polymers and advanced organic materials with unique properties.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and cross-coupling reactions.
• Fine Chemical Production: A critical reagent for manufacturing complex flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial R&D: Fundamental research tool in organic chemistry for studying ring strain, reaction mechanisms, and developing new synthetic methodologies.

Basic Information

Product Name	Cyclobutyl Chloride
CAS No.	1120-57-6
Molecular Formula	C4H7Cl
Molecular Weight	90.55 g/mol
Synonyms	Chlorocyclobutane; Cyclobutylchloride; Monochlorocyclobutane; Cyclobutane, chloro-; 1-Chlorocyclobutane; NSC 60548; Cyclobutanecarbonyl chloride (Note: this is a different compound, often confused); Cyclobutane chloride
EINECS	214-315-1

Quality Control

Our Cyclobutyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications, and our quality documentation is fully traceable.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at temperatures between 2°C and 8°C (refrigerated) to minimize evaporation and degradation. Keep away from strong acids, bases, and oxidizing agents. Containers should be kept tightly sealed and upright in a secondary containment area.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.0 g/mL
Boiling Point	~85-90°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.