Description

Methyl 4-Bromocrotonate is a versatile brominated ester building block, CAS NO 1117-71-1, prized for its reactive alkene and ester functionalities. It serves as a critical intermediate in the synthesis of complex molecules, enabling efficient carbon-carbon bond formation and functional group transformations. This high-purity reagent is essential for research and development in pharmaceuticals and agrochemicals, where it is used to construct active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring bromo-alkene motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides as a precursor for bioactive compounds.
• Organic Synthesis Reagent: Employed in Michael additions, cross-coupling reactions (e.g., Heck, Suzuki), and other palladium-catalyzed transformations.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialized polymers and advanced materials.
• Chemical Biology Probes: Utilized to create labeled compounds or probes for studying biological pathways and mechanisms.
• Flavor & Fragrance Industry: Intermediate for the synthesis of certain aroma chemicals and complex esters.

Basic Information

Product Name	Methyl 4-Bromocrotonate
CAS No.	1117-71-1
Molecular Formula	C5H7BrO2
Molecular Weight	179.01 g/mol
Synonyms	4-Bromocrotonic Acid Methyl Ester; Methyl (E)-4-Bromobut-2-enoate; (E)-Methyl 4-Bromocrotonate; 2-Butenoic acid, 4-bromo-, methyl ester; Methyl trans-4-Bromocrotonate; trans-Methyl 4-bromocrotonate; Methyl γ-bromocrotonate
EINECS	214-257-6

Quality Control

Our Methyl 4-Bromocrotonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Isomeric Purity (E-isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.