Description

17β-Hydroxy-5α-Androst-2-Ene-2-Carbonitrile is a high-purity steroidal nitrile derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its unique structure provides a valuable scaffold for the research and development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of specialized steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: A vital building block for medicinal chemists exploring new drug candidates targeting hormone receptors.
• Biochemical Research: Used as a reference standard or probe in studies of steroidogenesis and enzyme inhibition.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for high-value applications.

Basic Information

Product Name	17β-Hydroxy-5α-Androst-2-Ene-2-Carbonitrile
CAS No.	1093-60-3
Molecular Formula	C₂₀H₂₉NO
Molecular Weight	299.45 g/mol
Synonyms	17β-Hydroxy-5α-androst-2-ene-2-carbonitrile; 2-Cyano-5α-androst-2-en-17β-ol; 5α-Androst-2-ene-2-carbonitrile, 17β-hydroxy-; 17β-Hydroxy-2-cyano-5α-androst-2-ene; Androst-2-ene-2-carbonitrile, 17β-hydroxy-5α-; (5α,17β)-17-Hydroxyandrost-2-ene-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 17β-Hydroxy-5α-Androst-2-Ene-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.