Description

Phenylglyoxal Monohydrate is a versatile and highly reactive α-ketoaldehyde building block, essential for advanced organic synthesis and biochemical research. Its unique bifunctional structure makes it a critical reagent for introducing glyoxal moieties and for the selective modification of arginine residues in peptides and proteins. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors developing novel active ingredients, cross-linking agents, and diagnostic probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of heterocyclic compounds, including imidazoles and quinoxalines, with potential biological activity.
• Bioconjugation & Proteomics: Selective modification agent for arginine residues in peptides and proteins, used in protein structure-function studies, enzyme inhibition, and antibody-drug conjugate (ADC) development.
• Cross-linking Reagent: Used to create covalent cross-links in polymers, hydrogels, and biomaterials for controlled release and tissue engineering applications.
• Agrochemical Synthesis: Building block for creating novel fungicides, herbicides, and plant growth regulators.
• Fluorescent Probe Synthesis: Starting material for the preparation of advanced fluorescent dyes and sensors used in bioimaging and diagnostics.
• Organic Synthesis: Versatile reagent for Strecker synthesis and other condensation reactions to form complex molecular architectures.

Basic Information

Product Name	Phenylglyoxal Monohydrate
CAS No.	1075-06-5
Molecular Formula	C8H6O3 • H2O
Molecular Weight	168.15 g/mol (Anhydrous basis: 150.13 g/mol)
Synonyms	2-Oxo-2-phenylethanal Monohydrate; Phenacylformaldehyde Monohydrate; α-Ketophenylacetaldehyde Monohydrate; Benzoylformaldehyde Monohydrate; Oxophenylacetaldehyde Monohydrate; Phenylglyoxal Hydrate; Glyoxal, Phenyl-, Monohydrate
EINECS	214-062-8

Quality Control

Our Phenylglyoxal Monohydrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, water content, and impurity profile. Our quality commitment supports applications requiring high-purity reagents, from research and development to pilot-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	9.0 - 11.5%
Melting Point	90 - 95 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.