Description

(1S,4S)-4-(Methoxycarbonyl)Cyclohexanecarboxylic Acid is a high-purity, stereochemically defined chiral building block of significant synthetic value. Its rigid cyclohexane backbone and dual functional groups make it a versatile intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require reliable, high-quality chiral synthons for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic diseases.
• Asymmetric Synthesis: Used as a starting material or scaffold for constructing enantiomerically pure compounds via stereoselective reactions.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Peptidomimetics and Bioactive Molecules: Incorporated into the design of conformationally constrained peptide analogs and other bioactive molecules to enhance stability and potency.
• Advanced Material Research: Employed in the development of specialty polymers and liquid crystals where specific molecular geometry is critical.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(1S,4S)-4-(Methoxycarbonyl)Cyclohexanecarboxylic Acid
CAS No.	1011-85-4
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(1S,4S)-4-(Methoxycarbonyl)cyclohexane-1-carboxylic acid; (1S,4S)-4-Carbomethoxycyclohexanecarboxylic Acid; trans-4-(Methoxycarbonyl)cyclohexanecarboxylic Acid; (1S,4S)-Methyl 4-carboxycyclohexanecarboxylate; 4-Methoxycarbonyl-cyclohexanecarboxylic acid, (1S,4S)-; Cyclohexanecarboxylic acid, 4-(methoxycarbonyl)-, (1S,4S)-; (1s,4s)-4-Methoxycarbonylcyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our (1S,4S)-4-(Methoxycarbonyl)Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.