Description

3-Phenyl-4,5-dihydro-5-isoxazolecarbonitrile is a versatile heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused isoxazoline ring, makes it a critical intermediate for constructing complex molecules with potential biological activity. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and agrochemical discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers with specific thermal or optical properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and cellular processes.

Basic Information

Product Name	3-Phenyl-4,5-dihydro-5-isoxazolecarbonitrile
CAS No.	1011-38-7
Molecular Formula	C10H8N2O
Molecular Weight	172.18 g/mol
Synonyms	5-Cyano-3-phenyl-4,5-dihydroisoxazole; 3-Phenyl-4,5-dihydroisoxazole-5-carbonitrile; 5-Isoxazolecarbonitrile, 4,5-dihydro-3-phenyl-; 3-Phenyl-2-isoxazoline-5-carbonitrile; 5-Cyano-3-phenyl-2-isoxazoline; 1011-38-7; NSC 163044
EINECS	Contact for details

Quality Control

Our 3-Phenyl-4,5-dihydro-5-isoxazolecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.