Description

2-Bromo-4-Chlorobutyrophenone is a halogenated aromatic ketone, a versatile and high-purity organic intermediate crucial for advanced chemical synthesis. Its value lies in its reactive bromine and chlorine substituents, which make it an essential building block for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for applications such as the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic ketone motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its halogen atoms facilitate further functionalization.
• Fine Chemical Production: Serves as a precursor for other specialty chemicals, including liquid crystals, dyes, and advanced polymer materials.
• Organic Synthesis Research: A valuable reagent in academic and industrial laboratories for methodology development, such as in cross-coupling reactions or nucleophilic substitution studies.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	2-Bromo-4-Chlorobutyrophenone
CAS No.	1011-26-3
Molecular Formula	C10H10BrClO
Molecular Weight	261.54 g/mol
Synonyms	1-(2-Bromo-4-chlorophenyl)-1-butanone; 2-Bromo-4'-chlorobutyrophenone; 4-Chloro-2-bromobutyrophenone; Butyrophenone, 2-bromo-4-chloro-; p-Chloro-o-bromobutyrophenone; NSC 404087; 2-Bromo-4-chlorophenyl propyl ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chlorobutyrophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place. Store under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.