Description

Cyclohexylphosphonic Dichloride is a versatile organophosphorus reagent characterized by its highly reactive dichloride functional group. This compound is critical for introducing the cyclohexylphosphonate moiety into target molecules, enabling the synthesis of complex phosphonic acid derivatives and organophosphorus compounds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from catalyst development to the creation of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting bone diseases, viral infections, and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, plant growth regulators, and pesticides that require specific phosphonate functionalities.
• Ligand and Catalyst Preparation: Serves as a precursor for phosphonate-based ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Flame Retardant Development: An intermediate in the synthesis of specialized organophosphorus flame retardants and plasticizers.
• Surface Modification Agent: Employed to create phosphonate monolayers on metal oxides for corrosion inhibition, lubrication, and biocompatible coatings.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new reactions in organophosphorus chemistry and material science.

Basic Information

Product Name	Cyclohexylphosphonic Dichloride
CAS No.	1005-22-7
Molecular Formula	C6H11Cl2OP
Molecular Weight	201.03 g/mol
Synonyms	Cyclohexylphosphonyl Dichloride; Cyclohexanephosphonic Dichloride; Dichloro(cyclohexyl)phosphine Oxide; Phosphonic Dichloride, Cyclohexyl-; Cyclohexylphosphonic Acid Dichloride; Cyclohexylphosphonoyl Dichloride; (Dichlorophosphinyl)cyclohexane
EINECS	213-719-5

Quality Control

Our Cyclohexylphosphonic Dichloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including GC/HPLC for purity, NMR for structural confirmation, and titration for assay to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.30 g/cm³
Refractive Index (n20D)	~1.485

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.